Tokbox, lets you talk with your friends over flash-based live video chat video, closes $4 million in a Series A round from Sequoia Capital and angel investors. TokBox has developed a product that allows people to easily talk face-to-face with anyone in the world in a single click. There’s no registration, download, installation, configuration or any other hassle. Founded by two young entrepreneurs Serge Faguet and Ron Hose.

Angel investors include the founders of YouTube, Netscape and Bebo; top executives at Slide, PayPal and Cisco; as well as the head of the graduate Computer Science program at Stanford University. The company will use the capital from its Series A to support rapid user growth, expand the team, and accelerate its efforts to simplify video communication.

“We’ve designed TokBox to be a very easy means for video calling and messaging,” said TokBox CEO Serge Faguet. “Our goal at TokBox is to make conversations online as rich an experience as the in-person communication we have offline.”

Due to its broad applicability, TokBox has grown rapidly and is already being used in a variety of ways: from college students and their parents communicating face-to-face from around the world, to music artists speaking with their fans on MySpace, to software development teams collaborating remotely. In addition to usage on TokBox.com, users can add a video communication element by embedding TokBox on relevant applications like blogs, social networks, and commerce and community sites.

“Although the concept of live video conferencing has been around for a long time, it has yet to take off because existing solutions have been too complex for the end-user,” said YouTube Co-Founder Jawed Karim. “TokBox is the first video communications product to eliminate this complexity, allowing millions of users around the world to easily have face-to-face video conversations.”

TokBox also lets users send videomails to anyone with an email address, and embed video communication into any website (e.g. blogs, social networks or dating sites).